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Identifikasi Mutu Simplisia dan Ekstrak Serta Uji Aktivitas Antioksidan Ekstrak Daun Sungkai (Peronema canescens Jack)
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Vol. 5 No. 2 (2025) • Articles

Identifikasi Mutu Simplisia dan Ekstrak Serta Uji Aktivitas Antioksidan Ekstrak Daun Sungkai (Peronema canescens Jack)

Published 2025-12-31
Muhammad Ma'ruf , Dwi Rizki Febrianti , Eka Kumalasari , Danang Prasetyaning Amukti , Blegoh Iwan Santoso
Jurnal Farmasi Klinik dan Sains , Vol. 5, No. 2 (2025) , pp. 64-77 , Published: 2025-12-31
1 Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Banjarmasin, Indonesia, 70123.
2 Fakultas Ilmu-Ilmu Kesehatan, Universitas Alma Ata, Bantul, Daerah Istimewa Yogyakarta, Indonesia, 55183.
3 Politeknik Unggulan Kalimantan, Banjarmasin, Indonesia, 70122.

Abstract

Sungkai (Peronema canescens Jack.) merupakan salah satu tanaman yang telah lama dimanfaatkan oleh masyarakat sebagai obat tradisional untuk berbagai jenis penyakit. Tanaman ini khususnya pada bagian daun diketahui mengandung flavonoid alkaloid saponin tanin dan terpenoid atau steroid yang berperan sebagai antioksidan. Namun data terkait variasi mutu simplisia dan ekstrak daun sungkai masih terbatas sehingga berpotensi memengaruhi konsistensi aktivitas dan kualitas produk herbal. Penelitian ini bertujuan untuk mengetahui kandungan kimia dalam simplisia dan ekstrak daun sungkai, serta menguji kemampuan antioksidannya dengan metode DPPH. Penelitian ini diawali dengan pengambilan daun sungkai segar yang kemudian diolah menjadi simplisia dan diekstraksi menggunakan etanol 96% melalui metode maserasi. Karakterisasi simplisia dan ekstrak dilakukan melalui uji organoleptik, penetapan parameter spesifik dan nonspesifik, serta skrining fitokimia. Uji aktivitas antioksidan dilakukan dengan metode DPPH menggunakan vitamin C sebagai pembanding serta mengacu pada kriteria klasifikasi nilai ICâ‚…â‚€ untuk menentukan tingkat kekuatan aktivitas antioksidan. Hasil penelitian ini menunjukkan bahwa simplisia dan ekstrak daun sungkai mengandung alkaloid, flavonoid, saponin, tanin, serta terpenoid/steroid. Parameter mutu simplisia memenuhi standar Farmakope Herbal Indonesia. Uji DPPH menghasilkan nilai ICâ‚…â‚€ vitamin C sebesar 7,80 ppm dan ekstrak daun sungkai sebesar 14,55 ppm. Keduanya termasuk kategori aktivitas antioksidan sangat kuat, meskipun ekstrak daun sungkai sedikit lebih rendah dibanding vitamin C. Temuan ini menunjukkan bahwa daun sungkai berpotensi dikembangkan sebagai sumber antioksidan alami serta menjadi dasar dalam upaya standardisasi bahan baku dan pengembangan sediaan herbal.

Keywords

daun sungkai fitokimia antioksidan DPPH
Copyright (c) 2025 Muhammad Ma'ruf, Dwi Rizki Febrianti, Eka Kumalasari, Danang Prasetyaning Amukti Amukti, Blegoh Iwan Santoso3 Santoso

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