Journal Information
KENDALA RETENSI TERAPI ANTIRETROVIRAL (ARV) PADA PASIEN HIV/AIDS DI RSUD DR MOEWARDI (RSDM) SURAKARTA JAWA TENGAH
Eka Febriyanti, Diani Mega Sari, Ghalib Syukrillah Syahputra, Nahrul Hasan, Ayu Amelia, Rastria Meilanda
= https://doi.org/10.26753/jfks.v4i1.1365 
Abstract views = 99 times
|
views = 1 times
Abstract
Terapi Antiretroviral (ARV) bertujuan untuk mengurangi risiko penularan HIV/AIDS, menghambat perburukan infeksi oportunistik, meningkatkan kualitas hidup Orang DenganHIV/AIDS (ODHA) dengan menurunkan jumlah viral load dan meningkatkan jumlah CD4. Kunci keberhasilan terapi ARV adalah mempertahankan retensi. Lost To Follow Up (LTFU) dan kegagalan pengobatan menjadi kendala bagi ODHA dalam mencapai keberhasilan pengobatan ARV. Penelitian ini bertujuan untuk mengetahui prediktor hambatan mendapatkan retensi pengobatan ARV. Penelitian ini menggunakan rancangan case control dengan jumlah sampel 100 responden. Analisis data dilakukan dengan menggunakan metode chi-square. Hasil analisis bivariat, prediktor buruknya retensi berdasarkan persepsi pasien terhadap hambatan menjalani terapi ARV adalah kendala biaya transportasi (p=0.002; COR=8.34), kendala jarak perjalanan ke RSDM (p=0.002; COR=5.06), hambatan kesibukan lainnya (p=<0.001; COR=6,64), memiliki Pengawas Menelan Obat (p=0.003; COR=6.64), mengungkapkan status ODHA kepada orang lain (p=0.004; COR= 12.25), dan stigma (p=<0.001; COR= 12,3). Berdasarkan hasil uji multivariat persepsi pasien terhadap hambatan dalam menjalankan terapi ARV yang paling berdampak pada buruknya retensi terapi adalah mengungkapkan status ODHA kepada orang lain (AOR=13.1; p=0.042).
Keywords
References
Adelekan, B., Andrew, N., Nta, I., Gomwalk, A., Ndembi, N., Mensah, C., … Aliyu, A. (2019). Social barriers in accessing care by clients who returned to HIV care after transient loss to follow-up. AIDS Research and Therapy, 16(1), 1–7. https://doi.org/10.1186/s12981-019-0231-5
Adeniyi, O. V., Ajayi, A. I., Goon, D. Ter, Owolabi, E. O., Eboh, A., & Lambert, J. (2018). Factors affecting adherence to antiretroviral therapy among pregnant women in the Eastern Cape, South Africa. BMC Infectious Diseases, 18(1), 1–11. https://doi.org/10.1186/s12879-018-3087-8
Akullian, A. N., Mukose, A., Levine, G. A., & Babigumira, J. B. (2016). People living with HIV travel farther to access healthcare: A population-based geographic analysis from rural Uganda. Journal of the International AIDS Society, 19(1), 1–8. https://doi.org/10.7448/IAS.19.1.20171
Bilinski, A., Birru, E., Peckarsky, M., Herce, M., Kalanga, N., Neumann, C., … Keck, J. (2017). Distance to care, enrollment and loss to follow-up of HIV patients during decentralization of antiretroviral therapy in Neno District, Malawi: A retrospective cohort study. PLoS ONE, 12(10), 1–13. https://doi.org/10.1371/journal.pone.0185699
Bulsara, S. M. (2016). Predictors of Adult Retention in HIV Care : A Systematic Review. AIDS and Behavior. https://doi.org/10.1007/s10461-016-1644-y
Guo, D. W. Y., & Jones, D. L. (2014). Risk and Protective Factors for Retention in HIV Care, 1483–1491. https://doi.org/10.1007/s10461-013-0633-7
Kemenkes RI. (2018a). Laporan Nasional RKD2018 FINAL. Badan Penelitian Dan Pengembangan Kesehatan. Retrieved from http://labdata.litbang.kemkes.go.id/images/download/laporan/RKD/2018/Laporan_Nasional_RKD2018_FINAL.pdf
Kemenkes RI. (2018b). Situasi Umum HIV/AIDS dan Tes HIV. Jakarta: Pusat Data dan Informasi Kementerian Kesehatan RI.
Koirala, S., Deuba, K., Nampaisan, O., Marrone, G., Ekström, A. M., Satti, A., … Hien, N. (2017). Facilitators and barriers for retention in HIV care between testing and treatment in Asia- A study in Bangladesh, Indonesia, Lao, Nepal, Pakistan, Philippines and Vietnam. PLoS ONE, 12(5), 1–20. https://doi.org/10.1371/journal.pone.0176914
Makurumidze, R., Mutasa-Apollo, T., Decroo, T., Choto, R. C., Takarinda, K. C., Dzangare, J., … Rusakaniko, S. (2020). Retention and predictors of attrition among patients who started antiretroviral therapy in Zimbabwe’s national antiretroviral therapy programme between 2012 and 2015. PLoS ONE, 15(1), 28–42. https://doi.org/10.1371/journal.pone.0222309
Mekuria, L. A., Prins, J. M., Yalew, A. W., & Sprangers, M. A. G. (2015). Retention in HIV Care and Predictors of Attrition from Care among HIV-Infected Adults Receiving Combination Anti-Retroviral Therapy in Addis Ababa, 1–15. https://doi.org/10.1371/journal.pone.0130649
Mohammedaman, M., Manilal, Aseer, Tesfa, Haile, Mohammed, … Erbo, E. (2018). Prevalence of Pulmonary Tuberculosis and Associated Factors Among HIV Positive Patients Attending Antiretroviral Therapy Clinic at Arba Minch General Hospital, Southern Ethiopia. The Open Microbiology Journal, 12(1), 163–171. https://doi.org/10.2174/1874285801812010163
Mwale, J. C. (2016). Factor Affecting Retention In Care of Patient on AntiRetroviral Treatment in THe Kabwe District, Zambia, (June).
Ngugi, A. K., Agoi, F., Mahoney, M. R., Lakhani, A., Mang’Ong’o, D., Nderitu, E., … Macfarlane, S. (2017). Utilization of health services in a resourcelimited rural area in Kenya: Prevalence and associated household-level factors. PLoS ONE, 12(2), 1–12. https://doi.org/10.1371/journal.pone.0172728
Nyoman, N., Wardani, T., Ayu, K., & Sari, K. (2018). PREDIKTOR KEPATUHAN PENGGUNA ANTIRETROVIRAL PADA ORANG DENGAN HIV / AIDS LELAKI SEKS DENGAN LELAKI DI KLINIK BALI MEDIKA TAHUN 2013 & 2014 Program Studi Pendidikan Dokter , 2 Bagian IKK / IKP Fakultas Kedokteran Universitas Udayana Human immunodeficiency , 7(8).
Pruitt, Z., Robst, J., Langland-Orban, B., & Brooks, R. G. (2015). Healthcare Costs Associated with Antiretroviral Adherence Among Medicaid Patients. Applied Health Economics and Health Policy, 13(1), 69–80. https://doi.org/10.1007/s40258-014-0138-1
Reddy, R., Murhekar, M. V, Bhatnagar, T., Uthappa, C. K., & Chava, N. (2014). Survival probability and predictors of mortality and retention in care among patients enrolled for first-line antiretroviral therapy , Andhra Pradesh , India , 2008 – 2011, 198–205. https://doi.org/10.1093/trstmh/tru025
Telele, N. F., Kalu, A. W., Marrone, G., Gebre-Selassie, S., Fekade, D., Tegbaru, B., & Sönnerborg, A. (2018). Baseline predictors of antiretroviral treatment failure and lost to follow up in a multicenter countrywide HIV-1 cohort study in Ethiopia. PLoS ONE, 13(7), 1–14. https://doi.org/10.1371/journal.pone.0200505
Thida, A., Thein, S., Tun, T., Ko, S., Zaw, K., Lover, A. A., … Clevenbergh, P. (2016). Retention and Risk Factors for Attrition in a Large Public Health ART Program in Myanmar : A Retrospective Cohort Analysis, 9(9). https://doi.org/10.1371/journal.pone.0108615
Weaver, E. R. N., Pane, M., Wandra, T., Windiyaningsih, C., Herlina, & Samaan, G. (2014). Factors that influence adherence to antiretroviral treatment in an urban population, Jakarta, Indonesia. PLoS ONE, 9(9), 1–7. https://doi.org/10.1371/journal.pone.01075
Wekesa, P., McLigeyo, A., Owuor, K., Mwangi, J., Nganga, E., & Masamaro, K. (2020). Factors associated with 36-month loss to follow-up and mortality outcomes among HIV-infected adults on antiretroviral therapy in Central Kenya. BMC Public Health, 20(1), 1–11. https://doi.org/10.1186/s12889-020-8426-1
Refbacks
- There are currently no refbacks.
Copyright (c) 2024 Eka Febriyanti
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
JFKS (e-ISSN: 2809-2899; p-ISSN: 2809-3828) is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Universitas Muhammadiyah Gombong
Address: Jl. Yos Sudarso No.461 Gombong, Kabupaten Kebumen, Jawa Tengah 54412.
Phone: (0287) 472433 | Email: jfks@unimugo.ac.id