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FORMULATION AND EVALUATION OF HANDSANITIZER GANITRI LEAVE EXTRACT (Elaeocarpus ganitrus Roxb)
Naelaz Zukhruf Wakhidatul Kiromah, Laeli Fitriyati, Sinta Wahyu Septiani
= https://doi.org/10.26753/jfks.v2i1.815 
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Abstract
Ganitri (Elaeocarpus ganitrus Roxb.) is one of the traditional medicinal plants that grows in Kebumen Regency, every part of the plant can cure various diseases. The leaves are known to contain carbohydrates, alkaloids, flavonoids, saponins, steroids, glycosides and anthraquinones which show antibacterial activity. Research on the development of pharmaceutical preparations from ganitri leaves has never been done. Seeing the large number of ganitri plants that grow and their great potential, this study aims to develop a pharmaceutical formulation in the form of a Hand Sanitizer.The results showed that formula 1 in the hand sanitizer spray preparation with a concentration of 1% ganitri (Elaeocarpus ganitrus Roxb.) leaf ethanol extract and 5% aloe vera had the best physical evaluation of the preparation. The data from the physical evaluation were analyzed statistically, namely the pH test and the viscosity test. The results of the normality test data and homogeneity test data with P> 0.05, which means that the data is normally distributed and homogeneous. The results of the ANOVA test showed that in the pH test there was no significant difference because the significance value was p> 0.05, while in the viscosity test the significance value was P < 0.05, it could be concluded that the average concentration of each formula in the viscosity test had a significant difference and systemically proven. Formulas 1, 2 and 3 had the diameter of inhibition against all test bacteria with the best inhibition in formula 2 of 18 mm on e.coli bacteria, 17.19 mm on s. aureus bacteria and 17 mm on shigella bacteria.
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References
Farmasi, A., & Denpasar, S. (n.d.). *Akademi Farmasi Saraswati Denpasar, Jalan Kamboja No 11A, Denpasar, Bali. 3(2), 61–70.
Indarto, Nurlita, W., Anggoro, bambang S., & Novitasari, A. (2019). Aktivitas antibakteri ekstrak daun binahong terhadap propionibacterium acnes. Jurnal Tradis Biologi, 10(1), 67–78.
Jayashree, I., Geetha, D. H., & Rajeswari, M. (2016). Evaluation of Anti-Microbial Activity of Elaeocarpus tuberculatus Roxb . 16(11), 1726–1731. https://doi.org/10.5829/idosi.aejaes.2016.1726.1731
Jayashree, I., & Nadu, T. (2014). EVALUATION OF ANTIMICROBIAL POTENTIAL OF ELAEOCARPUS SERRATUS L. International Journal of Pharmaceutical Sciences and Research, 5(8), 3467–3472. https://doi.org/10.13040/IJPSR.0975-8232.5(8).3467-72
Kusnadi, K., & Devi, E. T. (2017). Pancasakti Science Education Journal. 2(9), 56–67.
Lukas, A. (2012). Formulasi Obat Kumur Gambir dengan Tambahan Peppermint dan Minyak Cengkeh. 23(2), 10.
Maulida, R., & Guntari, A. (2015). TERHADAP RENDEMEN EKSTRAK DAN KANDUNGAN TOTAL ANTOSIANIN THE INFLUENCE OF PARTICLE SIZE OF BLACK RICE ( Oryza sativa L .) ON EXTRACT YIELD AND TOTAL ANTHOCYANIN. 0, 9–16.
Pandey, K., Singh, M., Pandey, B., Upadhyaya, A., & Pande, K. K. (2016). Preliminary phytochemical screening and antimicrobial activities of plant extract of Elaeocarpus ganitrus Roxb . 4885–4889.
Putri, S. (n.d.). (Balai Penelitian Teknologi Perbenihan Bogor). 1991, 1–10.
Rashmi, P., & Amrinder, K. (2014). Mythological and Spiritual Review on Eloeocarpus Ganitrus and Assessment of Scientific Facts for its Medicinal Uses Key Words : 5, 334–353.
Rohandi, A. (2014). Sebaran populasi dan potensi tanaman ganitri (Elaeocarpus ganitrus Roxb.) di Jawa Tengah. Jurnal Ilmu Kesehatan, 8(1), 25–33.
Rohandi, A., & Gunawan. (2014). Distribution of Population and Potentials of Ganitri Trees (Elaeocarpus ganitrus Roxb) In Central Java. Journal of Forestry Sciences, 8(1), 25–33.
Septiani, S. W., Zukhruf, N., Kiromah, W., & Rahayu, T. P. (2020). UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN GANITRI ( Elaeocarpus ganitrus Roxb .) DARI Salmonella typhi. 1–8.
Sinuraya, Z. (2017). Karakteristik Kimia Minyak Ganitri ( Elaeocoarpusganitrus ROXB ) Hasil Ekstraksi. Jurnal Penelitian Pangan, 1(1), 40–43. https://doi.org/10.24198/jp2.2016.vol1.1.
Syarif, U. I. N., Jakarta, H., Melian, E., Kesehatan, F. I., & Farmasi, P. S. (2018). Uin syarif hidayatullah jakarta.
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